Shanghai Endi Biotechnology Co., Ltd
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    502, Building D11, Chuangyan Zhizao, Lane 3188, Xiupu Road, Pudong New Area, Shanghai
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Symphony X peptide synthesizer
Symphony X peptide synthesizer
Product details

Product advantages and features

HeatableRVs, Improve the synthesis of difficult compounds

real timeUV detection

Oscillatory mixing,N2 spray

Synthetic purity higher than80% or 90%

27 amino acids+an additional 6 amino acid positions

Integrate automatic cutting function without the need for third-party instruments

uniquePeptide Predictor function

Before synthesis, the software predicts the difficulty level of each amino acid synthesis and uses a graph to show that the software can simulate the synthesis process. After confirming the accuracy, reagents are added for synthesis
Save reagents, simplify experimental design difficulty, optimize synthesis conditions, and increase success rate

Matrix Liquid Transfer Technology Each channel is completely independent

Optimized liquid rapid transfer mode
Zero dead volume ensures comprehensive and effective synthesis, avoiding reagent waste
Thoroughly flushing the matrix and transmission pipelines ensures that reagents do not cross infect

IntelliSynth ™ UV online monitoring and feedback technology

Real time: Each step of the synthesis process is sampled and monitored multiple timesTake a sample every 10 seconds
Online: InternalThe UV detector is located below the sampler, and immediately detects the results after taking a small sample
Feedback: The program analyzes the results of multiple sampling tests and only proceeds to the next step if it considers the deprotection to be complete

Single Shot Technology

need notPriming, Extract all amino acid reagents at once
Specially suitable for expensive non natural special amino acids
Plug and play, precise control of usage, eliminating waste

Super shock mixing and inert gas protection

Mechanical mixing and nitrogen bubbling stirring are used simultaneouslyEnsure sufficient contact between resin and reactants
Continuously immerse the resin in the reaction solution to achieve rapid and high-quality synthesis
All reagentsThe reaction device and liquid transfer pipeline are all protected by nitrogen gas, effectively avoiding the occurrence of side reactions

Infrared heating module and induction heating method

Fast, precise, and uniform heatingThe temperature ranges from 25-90 degrees Celsius and can reach the desired temperature in a few seconds
Not damaging amino acid modifying groupsAnd reduce by-products
Controllable switchMeet the need for heating only in special synthesis processes

The peptide can be automatically cleaved in situ after synthesis or during synthesis

No need to purchase additional cutting equipment
Improve yield
Automatic cleaning after cutting
Adjustable start time

Complete security response

When there are problems in the subsequent synthesis, priority should be given to ensuring the quality of the previously successfully synthesized parts
Perform automatic emptying and cleaning process on the synthesized parts, and issue warnings via email or SMS
Subsequently, by adjusting the reagents and procedures, the next step of synthesis can be continued on the basis of the already synthesized one, without causing waste

Stable equipment, high compatibility, and comprehensive after-sales service

supportFmoc, t-Boc, organic, peptid, combinatorial, branched, PNA, etc
deviceto the fullAvoid movable components and chemical corrosion resistant design
Real time monitoring of fluid system sensors

application:

High end tools for peptide drug development, vaccine production, marine drug research, and organic chemical synthesis

Specifications:

Number of reaction vessels 24 (12 with pre activation option), no resin loader required

Synthetic scalerange 0.005-24 mmol (up to approximately 2 g resin per RV)

Reaction vessel volume plasticsDisposable: 10ml, 45ml, borosilicate glass: 10ml, 40ml

Solvent location/Size 1 main solvent location, 20 liter capacity

7 solvent locations determined by users, ranging from 0.5 liters to 4 literscapacity, canProvide moreLarge capacity container

Number of amino acid positions up to40 amino acid positions

10ml, 120ml, and 400ml bottles

Supported Chemicals Fmoc、t-Boc、 Organic, protein like, combination, branched chain PNA

activation in situ activationHBTU, HATU, HCTU, TBTU, PyBOP, PyOxim, DIC/OxymaPure, DIC/HOBt, DIC/Oxyma-B, and others

throughput User defined

Fluid measurement technology Using optical sensors for fixed loop measurement

fluidtransmission method Positive pressure with nitrogen; top-down communicationpay

Mixing method Nitrogen bubbling and/Or eddy current mixing can be adjusted and programmed

division Automated vehicle cutting, independent fluid path and inlet/outlet

waste container one20 liter container with superfluid sensor

control interface properSymphony X control software, built-in CPU, and touchscreen display

report Real time recording of the functions of each instrumentPrint to a file or printer. Can be printed. Create PDF files for each method.

startKIT 40 pre packaged AA bottles (20 natural amino acids; 5 mmol and 20 mmol scales), reaction vessels (Prelude disposable RV, 30 packs of 10 mL and 30 packs of 45 mL RV), Rink Amide Resin (0.1 mmol scale), Fmoc Gly Wang Resin (0.1 mmol scale) HCTU(100 g)、 Activation agent sample kit (5g each for K-Oxyma, PyOxym, OxymAPure, and HDMA). The goods shipped to the United States also include 20% piperidine/DMF and 0.4M N-methylmorpholine/DMF (0.9L each) reagents. (Category number: SYMX-STARTKIT)

power supply 115 V/60 Hz or 230 V/50 Hz

size(WxDxH) 45 "x 29" (114 cm x 74 cm x 168 cm)

weight make an appointment550 pounds (250 kilograms)

warranty a year, parts andwork.

Optional heating Infrared radiation(IR heating (category number: SYMX-IR-OPT)

optional-UV monitoring Real time UV monitoring and feedback control system and software (catalog number:SYMX UV OPT)

optional-Software E-mail-Text message status report (category number: SYMX-TXT-EML-RP)

Number of reaction vessels

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Successful operation!

Successful operation!

Successful operation!